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Similar to apoptosis, we suggest that the enhanced autophagy that occurs in PAECs during the early stages of PH is insufficient to compensate for the impairment in response to environmental factors when environmental stress persists

The logic for their use in PD stems from the growing evidence that GD and altered GBA communication contribute to the disease pathogenesis

The role of miRNAs in cancer: from pathogenesis to therapeutic implications

The DSIP nonapeptide is engineered for researchers studying the intersection of neuroendocrinology and physiological recovery

Metabolically, TiO 2 NP exposure disrupts critical bacterial pathways including energy metabolism, detoxification, amino acid metabolism and SCFA production, which are vital for maintaining gut barrier integrity and regulating host energy homeostasis (Utembe et al., 2022

However, current clinically approved agents, such as Ivosidenib [152,153,154], function by reversing the mutated IDH1 phenotype, thereby attenuating the tumors acquired sensitivity to PARP inhibition