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However, neurons can also actively contribute to inflammation, creating a bi-directional relationship where neurons are both recipients and instigators of inflammation (177)

In diabetes, elevated FA storage increases myocardial diacylglycerol (DAG) concentrations, a signalling molecule that activates protein kinase C theta (PKC)

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This inhibitory effect is mediated by altering signal pathways like NF-B, JAK/STAT, MAPK/ERK that are involved in the production and release of cytokines and chemokines

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