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Monitoring thiopurine metabolites and enzymatic activity allow personalized dosing in IBD cases that started therapy and what is our knowledge of pharmacogenetic biomarkers as predictors prior to therapy, such questions will be discussed in this review

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Over the past few years, results from clinical trials of IMiDs in MM patients have shown that the presence of conferring resistance mutations, loss of gene copy and splice variants of cereblon are associated with resistance to IMiDs and worse clinical outcome 192,193

Half of Kidney Transplant Candidates Who are Older Than 60 Years Now Placed on the Waiting List Will Die Before Receiving a Deceased-Donor Transplant

(Hoboken) 304, 901913

doi: 10.1016/j.fct.2017.08.020