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Decoys can be used as therapeutic agents, either to inhibit the expression of genes that are activated by a transcription factor, or to upregulate genes that are suppressed by the binding of a transcription factor

Moreover, Ido1 is induced by the pro-inflammatory cytokine interferon gamma, whereas anti-inflammatory cytokines including IL-10 and transforming growth factor (TGF) inhibit Ido1, thus, activity of Ido1 in IECs reflects the balance between pro- and anti-inflammatory signals 171

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Vitamin C's soothing action on the skin can be helpful for rosacea, as can the anti-redness benefits of glutathione and ergothioneine

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NIH data shows that 3.6% of adults have vitamin B12 deficiency, and for these individuals, injections can be transformative