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The use of 3 H-Hinge to probe the interaction was based on the ability of 3 H-Hinge to bind specifically and with high affinity to HGF (Kawas et al., 2011)

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This article shows that activation of hypothalamic GIPR cells/neurons decreases food intake

For gastrointestinal use, it is commonly discussed for gut irritation, gastritis-type symptoms, reflux-type irritation, inflammatory gut symptoms, and mucosal support

The downstream consequences include enhanced glucose uptake into skeletal muscle independent of insulin, increased fatty acid oxidation, and suppression of inflammatory signaling

Possible clinical applications include assisting with healing after hysteroscopy, c-section, or intrauterine interventions