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Description

Safety and efficacy of INCB018424, a JAK1 and JAK2 inhibitor, in myelofibrosis

Vitamin A in nature

PMID: 27013460

Blanarova C, Galovicova A, Petrasova D

AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation

In multiple murine models of kidney fibrosis (e.g., UUO, adenine diet, I/R, 5/6 nephrectomy, folic acid), key ferroptotic features such as iron overload, oxidative stress, GPX4 downregulation, and ACSL4 upregulation are consistently observed