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Biochim Biophys Acta (2016) 1861(5):41929

Evidence of efficacy: Iron supplementation appears beneficial when an iron deficiency or low ferritin is present

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Repurposing the NRF2 activator dimethyl fumarate as therapy against synucleinopathy in Parkinsons disease

That just means you need either water or fat to break down and absorb the vitamins