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ATP production ATP production rates were measured in muscle and heart isolated mitochondria using an extended version of the hexokinase clamp that also includes NADP + and glucose-6-phosphate dehydrogenase (G-6-PDH) modified from a previous publication (Fig

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Leucine-rich repeat kinase 2 (LRRK2) is an important factor involved in the etiology of PD, LRRK2 mutations are the major reason of inherited and sporadic PD, and overexpression of miR-205 showed an association with the abnormal upregulation of LRRK2 in PD brains [53]