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Pb GS (R): 5-GCCC AGATCT TTAAGATCCATAATACATGATAAATTCAGAAGG-3

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By delivering localized and precise action, nanozymes minimize systemic side effects, while their integrated intelligent response features dynamically adjust therapeutic effects based on the wound state, significantly increasing treatment accuracy and sustainability [204], which makes up for the shortcomings of traditional methods

LEfSe also identified several discriminative features of intestinal microecological dysregulation in PSO, including Lachnospiraceae_NK4A136_group , Muribaculaceae , Bacteroides , Alloprevotella , Clostridia_vadinBB60_group , Roseburia ( Figure 5G ), which could potentially serve as markers for distinguishing between different tissues affected in PSO

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