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Although we have extensive knowledge of the location of cysteine modifications in individual proteins, we lack a functional understanding and interplay of the various cysteine modifications in a single protein and their consequences on the global scale

Mol Cell (2020) 78(6):101933

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Acitretin, on the other hand, carries an increased risk of hepatotoxicity when combined with alcohol, as it converts into etretinate, the more toxic and persistent metabolite