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It is generally believed that copper deposition can induce apoptosis through endoplasmic reticulum stress, mitochondrial autophagy, and oxidative stress ( in vitro studies have shown that copper stress mainly causes copper death rather than apoptosis and iron death, more in vivo studies, including our study, have shown that apoptosis and other death modes exist simultaneously in vivo

2024;36:76277.e9

Why Some Injuries Refuse to Heal Some tissues heal slowly because they have fewer blood vessels from the start

Although there was no significant increase in TNFA expression at this early stage, we noted a marked decrease in its expression 120 min after stimulation with serum from both severe and convalescent patients compared to that from HV

Grek, C