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Front Endocrinol (Lausanne) 12:720723, 2021

Concomitant therapy with other drugs that are metabolized in the liver may reduce the clearance rates of the quinolone and the other drug

Furthermore, chronic systemic inflammation induces a state of anabolic resistance within the muscle tissue

As ulcerative colitis does not present in the small intestine, the primary site of Zn absorption, the complications with Zn absorption often found in Crohns disease are typically not a concern in ulcerative colitis