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Particular attention is given to interventions that enhance synaptic plasticity, activate intrinsic neuroprotective pathways, and promote functional network regeneration (Figure 2)

Weeks 12-16+: optimization and maintenance Beyond the 12-week mark, the rate of change typically slows as the body reaches a new equilibrium

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Improves Balance

Since H2AX is also phosphorylated during unperturbed S phase 31 , this drop may be caused by depleting the pool of S phase cells due to the G2 arrest

USA 96 : 41314136 Hoshino T, Nakamura H, Okamoto M, Kato S, Araya S, Nomiyama K, Oizumi K, Young HA, Aizawa H and Yodoi J (2003) Redox-active protein thioredoxin prevents proinflammatory cytokine- or bleomycin-induced lung injury