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Research suggests that AgNPs can cross the BBB and accumulate in the brain, leading to neurotoxicity and neuronal degeneration (Janzadeh et al., 2022)

The RNA sequenceing data that support the findings of this study have been submitted to the NCBI Gene Expression Omnibus under the accession code GSE143164

It has been interesting to study this group to control for all the factors that might otherwise be difficult to control

As such, this review highlights the urgent need for clinical trials targeting antiangiogenic therapies in neurodegenerative diseases, because without robust data from clinical studies, the efficacy and safety of such interventions remain speculative

Proc Nutr Soc 74(4):367377 Carbone S et al (2017) Dietary fat, sugar consumption, and cardiorespiratory fitness in patients with heart failure with preserved ejection fraction

Ottenwalder H, Simon P