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Our analysis points out that the central nervous system is particularly prone to ferroptosis because they contain a lot of PUFAs and high iron flow

10.1016/j.jsb.2011.08.006 [DOI] [PubMed] [Google Scholar] Kreuzer-Martin HW, Ehleringer JR, & Hegg EL (2005)

Oxidized glutathione (GSSG) is reduced to GSH, a reaction catalyzed by glutathione reductase (GSH-Rx)

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A multi-model approach was employed to comprehensively assess DEC efficacy

The potential of SLU-PP-332 as a "exercise mimetic" to increase energy expenditure and fat oxidation is unmatched, even if its mode of action differs from that of 5-amino-1MQ, which operates via NNMT inhibition and ERR activation, respectively