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3.4.3 Mechanistic insight Metformin mitigates DOX-induced cardiotoxicity through both AMPK-dependent and -independent mechanisms

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We describe an inverse relationship between MYC and GCLC, the ratelimiting enzyme of GSH biogenesis, in a mouse model of MYCdriven liver cancer

The polylactic-glycolic acid copolymer formed by curcumin has 40-fold increased bioavailability compared to curcumin alone in rats 229 , 292

25 Clinical manifestations Neurological symptoms in WD typically begin in the second or third decade

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