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One pathway creates NAPQIa reactive compound that needs to be neutralized quickly

Fasting for 36 h was shown to increase cerebral blood flow (CBF) in most human brain regions, although there were a few brain regions that showed increased CBF with satiation (Tataranni et al., 1999)

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The authors also thank Michael V Sofroniew (University of California Los Angeles) for providing the GFAP-Cre mice, and Shigeyoshi Itohara for providing CaMKII-Cre mice