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There are two main caspase-dependent apoptotic pathways of apoptosis: the intrinsic pathway and the extrinsic pathway

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Methods In the current study, rat and mouse diabetic model were established, the left ventricular function of rat and mouse were evaluated by echocardiography and the fibrosis of rat ventricle was evaluated by Masson staining

Phosphoinositide 3-kinases (PI3Ks) belong to a family of phosphoinositide kinases, which can be divided into three classes: class I, class II, and class III PI3Ks [134]