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Rehabil 2022, 4 (2), e393e402

J Biol Chem 270:1567515685

doi: 10.3390/cells10061368 197 ZhangYMQiYBGaoYNChenWGZhouTZangYet al

found that nicotine can mediate the pyroptosis of aortic endothelial cells and exacerbate the formation of atherosclerotic plaques by constructing an ApoE-/- mouse atherosclerosis model (93)

In short, the feasibility and efficacy of MSCs in the treatment of radiation-induced fibrosis in humans are difficult to be confirmed in the short term