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| Real Peptides Research published in 2021 identified NNMT (nicotinamide N-methyltransferase) as a metabolic checkpoint enzyme

PE-22-28: A spadin analog with antidepressant and neurogenic effects

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Simultaneously, they suppress glucagon secretion (which normally raises blood glucose), slow gastric emptying to reduce post-meal glucose spikes, and act on appetite centres in the brain to promote satiety and reduce food intake