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The identification of therapeutic targets and biomarkers related to efferocytosis provides a promising foundation for future research and the development of effective therapies for stroke recovery (Table 1)

McMahon M, Itoh K, Yamamoto M, Hayes JD

These include a limited ability to repair damaged elements due to the loss of protein expression during erythropoietic maturation, high levels of molecular O 2 bound to Hb, which results in an abundance of oxidants, and high levels of iron within the prosthetic group of Hb, which can cause ROS production via the Fenton reaction