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doi: 10.5115/acb.24.178

The extracellular effects include binding to neuronal GABA A and glycine receptors, with subsequent cellular hyperpolarization, and attenuation of N -methyl-D-aspartic acid (NMDA)-mediated glutamate excitotoxicity

The methionine cycle metabolites adjust very rapidly to the decreased methionine input reaching new steady states within a few hours

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AChE Activity In the prefrontal cortex, Doxorubicin and Cyclophosphamide treatment showed a significant increase in AChE activity compared to the control group by 1.8 folds