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Malondialdehyde (MDA) and 4-hydroxynonenal (HNE) (Figure 1), end products of lipid peroxidation, are discharged from destroyed hepatocytes into the space of Disse (Figure 2)

Marcotte, D

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An inappropriate diet can exacerbate renal excretion and elevate the risk of cardiovascular disease in individuals with diabetes [93]

Disease Prevention Cardiovascular disease Interest in garlic and its potential to prevent cardiovascular disease began with observations that people living near the Mediterranean basin had lower mortality from cardiovascular disease (88)

10.1073/pnas.012581799 Luo J, McMullen JR, Sobkiw CL, Zhang L, Dorfman AL, Sherwood MC, Logsdon MN, Horner JW, DePinho RA, Izumo S, Cantley LC: Class IA phosphoinositide 3-kinase regulates heart size and physiological cardiac hypertrophy