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It is found in human blood, where its levels drop as we age, and it has one of the broadest and most independently repeated research records of any copper peptide, especially in skin and collagen studies

Mucosal Immunol 6:666677

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Research has also documented Semax-induced upregulation of nerve growth factor (NGF) mRNA in both rat hippocampus and in glial cell cultures suggesting that neurotrophin upregulation by Semax extends beyond the BDNF axis to encompass the broader neurotrophin family