glutathione ncbi

glutathione ncbi Glutathione! Glutathione: Pharmacological aspects and implications

Name: glutathione ncbi Glutathione! Glutathione: Pharmacological aspects and implications
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Tanshinone IIA protects human coronary artery endothelial cells from ferroptosis by activating the NRF2 pathway

Ottria et al

Nature 599 , 102107 (2021)

Tuxhorn JA, McAlhany SJ, Dang TD, Ayala GE, Rowley DR

Mitochondria are the cells powerhouses, crucial for energy production

The -cyano amide-based Michael acceptors have also been elegantly used by the Taunton group as warheads in small-molecule inhibitors to react with active site cysteines while being minimally affected by the high concentration of intracellular GSH due to the fast reaction kinetics and the mM of K d (refs 31, 32)