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Unlike exogenous GH administration which bypasses the pituitary entirely and suppresses endogenous GH production via negative feedback on the hypothalamic-pituitary axis MK-677 recruits the endogenous pituitary machinery, theoretically preserving somatostatin-mediated feedback regulation

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Etoposide (140mg/m2 iv.once weekly) + dexamethasone (10mg/m2/d p.o.) was started immediately

The combination is heavily discussed in communities like Reddits r/Peptides, but personal reports however numerous are not controlled data

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