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Genetic variants in NPC1L1 , regulating cholesterol absorption in the canalicular membrane and in the enterocyte in humans might also be involved in in cholesterol hypersecretion, although studies with the specific NPC1L1 inhibitor ezetimibe argue against this possibility [3944] and need to be further investigated

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Dont exceed the recommended daily dosage

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However, it is in the interest of consumers to know that despite the rarity of adverse events in response to dietary supplementation, there are still no safety requirements for manufacturers in Europe and the United States to market their supplements

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