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Approximately one third of patients with schizophrenia are considered to be treatment resistant [5], with the majority of these (2334%) failing to respond appreciably to dopamine-blocking antipsychotic medications from their first episode of psychosis (FEP) [6, 7]

Environmental changes lead to oxidative stress, resulting in disruptions in plant development and potentially leading to plant death (Sharma et al

and C.W., J.S., X.Q., Z.-Y.Y., and J.Y.-J.S.: wrote the manuscript

In contrast, MK-677 is a non-peptide compound with a longer half-life and excellent oral bioavailability