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If the hemoglobin level is less than 9 g/dL and evidence indicates persistent brisk hemolysis (hemoglobinuria), immediate blood transfusion is also indicated

Reeves et al., 1995

A vitamin B12 deficiency might cause various neurologic and also psychiatric disruptions

Xu WX, Zhang L, Mai JT, Peng RC, Yang EZ, Peng C, et al

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additionally, the mitochondrial ROS eventually translocate into the nuclei of BSO-treated cells in large aggregates