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5 Chitosan (CH) as a potential drug carrier Researchers in medical engineering are drawn to chitosan-based bio-materials as prospective carriers owing to their superior chemical, cellular, and mechanical properties that facilitate cell adhesion, growth, and division (Supernak et al., 2023)

391 Recessive POLG mutations can be homozygous or compound heterozygous, with compound heterozygous mutations in trans often associated with a more severe and earlier-onset phenotype, whereas homozygous recessive mutations tend to result in a milder and later-onset presentation

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Worsening of seizures after asparagine supplementation in a child with asparagine synthetase deficiency

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