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Black dots highlight proteins that meet both significance thresholds

In contrast, when histamine is released during the digestive process, binding to the H2 receptor stimulates a different GPCR-mediated cell signaling pathway that results in release of HCl into the gastric lumen

doi:10.1016/S0140-6736(09)60551-1

Closely associated with cardiometabolic disease, NAFLD is an independent risk factor CVD (92) , and a prevalent co-morbidity of type 2 diabetes (93) , with recent estimates suggesting 4764 % of individuals with type 2 diabetes have NAFLD globally (94)

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