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doi:doi: 10.1016/s0090-4295(03)00567-3 Prajapati, D., Rampal, K., Ali, I., Rangera, M., Chaurisia, S., & Prajapati, J

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The difference comes down to one critical factor most hangover guides ignore: first-pass metabolism destroys nearly all oral glutathione before it reaches circulation, while IV delivery bypasses the gut entirely