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Tagrisso is specifically indicated for people with exon 19 deletions or exon 21 mutations

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Table 1: Dose Reduction for Pemetrexed (single-agent or in combination) and Cisplatin- Hematologic Toxicities If patients develop nonhematologic toxicities (excluding neurotoxicity)=Grade 3, treatment should be withheld until resolution to less than or equal to the patients pre-therapy value