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[4] [6] The direct delivery of ascorbic acid into the bloodstream allows for supraphysiological concentrations, which could have distinct biological effects, such as pro-oxidant activity in the presence of transition metals or selective cytotoxicity against certain malignant cells, although these applications remain under investigation and are not universally accepted as standard of care

This route of administration can be particularly beneficial for patients who have difficulty swallowing oral medications or for those where oral administration is not optimal due to gastrointestinal issues

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The 10 patients with severe tibial plateau fractures had no history of keen pain and no evidence of OA on imaging examination

Giacchetti S, Perpoint B, Zidani R, Le Bail N, Faggiuolo R, Focan C et al

Lost in transgenesis: a users guide for genetically manipulating the mouse in cardiac research