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However, the induction of ferroptosis has a dual role in tumor growth

The reduced norepinephrine release may be beneficial also in other conditions with sympathetic hyperactivity such as heart failure and myocardial infarction in addition to the sparing effect of 1 -blockers on cardiac work load and energy consumption

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The significant reduction in oxygen uptake and the tendency to achieve lower blood lactate concentrations at the final ergometric load (VO2peak) during fasting observed in our study are also likely related to lower maximum power output and shorter exercise test duration