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stage 3 n = 476)

doi: 10.1038/s41584-022-00793-5 11 HasegawaTKikutaJSudoTMatsuuraYMatsuiTSimmonsSet al

It acts on spots, wrinkles and crows feet, providing elasticity to the fibers of the dermis

However, there are no specific histopathology features for morphea and routine histopathology can neither differentiate among the various types nor to distinguish it from SSc (95)