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Systemic amyloidosis is commonly associated with plasma cell dyscrasias, chronic inflammatory conditions, dialysis, or hereditary disorders, with the GI tract being one of several organs affected by amyloid deposition

Biological analyses were performed on serum, measuring folate, vitamin B12, homocysteine, and folate receptor-alpha autoantibodies using radioimmunoassay and mass spectrometry

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TGF-1 induced EMT increases the intracellular levels of unstable iron and ROS, and the elevated iron content and oxidative stress in cells undergoing EMT make them more susceptible to ferroptosis

Reduced GAD levels suggest decreased inhibitory signaling in the retina, causing larger photopic responses