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High variety of flavonoids and their modification (Williams and Grayer, 2004) and the absence of universality of flavonoid modifications in different plant species ( After completion of biosynthesis, secondary metabolites like GSLs and flavonoids, which are present at high concentrations in the cell, need to be imported into the vacuole ( Figure 2 , the identity is unknown), stored there or further metabolized and/or transported ( Figure 3 , transporters 16 and 17)

In addition, GSH regulates the balance of its production and utilization by feedback inhibition of the reaction catalyzed by GCL 33,35

Alpha arbutin gently blocks melanin production while vitamin C provides antioxidant protection and boosts collagen

[12] Glutathione deficiency can contribute to age-related health problems

Significance of differences between groups was determined by twotailed Student's t test or analysis of variance least significant difference test

The Pharmacokinetics of Vitamin C