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Circulation 142 , 22992311 (2020)

While no widespread anaphylactic reactions were reported in clinical trials, there has been an isolated case of a severe local hypersensitivity reaction characterized by intense redness, swelling, and urticaria (hives) at injection sites in a patient who developed anti-sermorelin antibodies

Dosing Protocol Considerations No standardized, peer-reviewed protocol exists for combining Retatrutide and Tesamorelin

Libido and skin quality improvements reported in some patients

Ipamorelin was originally developed by company Novo Nordisk, and was investigated in phase II clinical trials by Helsinn Therapeutics for treatment of postoperative ileus