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A previous in vitro study demonstrated that 7-day exposure of motor neurons to fluvastatin has less effects on spinal motor neurons in a dose-dependent manner (Murinson et al., 2012)

Moon YA, Horton JD

The possible mechanisms of ALC action in AD may also involve facilitating the rebuilding of cell membranes, as well as improving synaptic function, enhancing cholinergic activity, restoring the brain energy supply, protecting against toxins, and exerting neurotrophic effects via stimulating NGF and the acetylation of proteins [24]

Tejani, AM

IDH1 inhibition decreased the HTML:TML ratio, l-carnitine:TML ratio and acetylcarnitine:TML ratio in this extract without altering acetyl-CoA (Extended Data Fig

In newborns, common early symptoms are poor feeding, vomiting, lethargy, hyperventilation resulting often in respiratory alkalosis, and irritability that rapidly progresses to seizures, deep coma, and even death if not urgently treated