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doi: 10.3390/molecules28041861

[4] Urine vs Blood Blood provides direct hormone measurement, but urine is easier to collect

BBB dysfunction is an early pathophysiological change observed in nervous system diseases

Studies have shown that IECs in IBD patients exhibit decreased GPX4 expression and increased susceptibility to lipid peroxidation, leading to ferroptotic cell death, barrier dysfunction, and increased gut permeability (168, 169)