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Feature · Product Review
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Curcumin reduces Cyclin D1 protein expression, inhibiting cell cycle, particularly at the G0/G1 phase, in colon, breast, and prostate cancers

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It was shown that in the beginning of G1 phase of the cell cycle in animal cells, activation of oxidative processes in the cytoplasm caused by epidermal growth factor resulted in the accumulation of ROS, which activated phosphorylation cascades and DNA replication and induced cell division [32]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 32.Hayes JD, Dinkova-Kostova AT, Tew KD

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