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Once activated by oxidative stress, NRF2 translocates to the nucleus where it binds to antioxidant response elements (ARE) in the promoter region of genes involved in redox regulation, xenobiotic metabolism, DNA repair, apoptosis, proteostasis, and regulation of inflammation [9]

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One hundred milligrams of the powdered sample were extracted in 5 mL of 80% ethanol, followed by centrifugation at 5000 g for 10 min

Additionally, autoimmune disease also appears to be hallmarked by imbalanced glutathione levels