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We examine these issues using the SCALE phase 3a clinical trial program as an example and address how the use of estimands may help provide greater transparency in clinical trial reporting

The human evidence is much thinner than the social media narrative suggests

By 2 months posttreatment, there was decreased erythema and reduced scaling with the continued secukinumab therapy (eFigure 1)

When one gets cheek fillers, the nasolabial line will likely be smooth because you naturally stretch the face

Our findings support the evaluation of PRMT5 inhibitors in clinical trials, including their combination with cytotoxic and immune therapies

Lipase may support an evaluation for pancreatitis when characteristic abdominal pain is present