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Nevertheless, as these mice had a reduction in circulating IGF-1 and tissue IGF-1 expression

Based on these concepts, our lab has extensively investigated and characterized tumor metabolic pathways in hypoxic [hypoxia-inducible factor (HIF1)] and normoxic (oxidative phosphorylation) conditions ( This perspective review will explore the latest advances in targeting metabolic crosstalk with a particular focus on inhibiting the tryptophan-catabolized KP

Breast Cancer Res 13:R97 Sabatier R, Finetti P, Cervera N, Lambaudie E, Esterni B, Mamessier E, Tallet A, Chabannon C, Extra JM, Jacquemier J et al (2011) A gene expression signature identifies two prognostic subgroups of basal breast cancer

By confronting current limitations, such as interspecies metabolic differences and protocol variability, we outline a strategic roadmap for the field

doi: 10.1016/j.jhazmat.2017.10.014 46

46 (7), e14151