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In the current study, CPZ-DE and CPZ-RE groups demonstrated a marked upregulation in the mRNA expression of both NCOA4 and TfR1 and increase in TfR1 concentration compared to controls while there was a downregulation in FTH1 mRNA expression and decrease in ferritin concentration

In contrast to cytochromes P450, the active site of these enzymes is embedded in the lumenal part of ER

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But what if normal is simply a social agreement that changes across cultures, generations, and lived experiences

doi:10.1016/j.tibs.2019.04.001