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SFN involves the structural damage and degradation of the tiny, unmyelinated nerve fibers responsible for controlling autonomic functions like blood vessel constriction, sweating, and heart rate

10.1038/nn.4030 Nat Neurosci

Typically, these sporadic malignant schwannomas occur unpredictably without known familial predisposition (Plotkin & Blakeley, 2022)

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There was also a considerable dose-response relationship between LA and mean change in serum SICAM-l levels, while LA was generally well-tolerated and may reduce serum MMP-9 and sICAM-1 levels