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Remember, esters are weaker acylating reagents than either anhydrides or acyl halides, as noted earlier

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In particular, mice were monitored daily for signs of distress, including weight loss 20%, severe diarrhea, or irreversible morbidity, as predefined humane endpoints per institutional guidelines

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In the FY 2007 IPPS/LTCH PPS final rule (71 FR 48104), we codified at 412.320(a)(1)(iii) that hospitals reclassified as rural under 412.103 also are considered rural under the capital IPPS for purposes of determining eligibility for capital DSH payments