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Paludan and Bowie, 2013)

10.1016/j.heliyon.2023.e21711 61 HanL.ChenA.LiuL.WangF

Acknowledgements The cryo-electron microscopy data were collected at the Shanghai Advanced Center for Electron Microscopy, Shanghai Institute of Materia Medica, Chinese Academy of Sciences

29,30,31 The globally dedicated coronavirus disease Moonshot project, led by Frank von Delft et al., has advanced from the fragment screening of molecules binding to the SARS-CoV-2 main protease (M pro ) to the identification of the clinical candidate DNDI-6510 in just 18 months