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617 The metabolite -KG from glutamine breakdown has been identified as a crucial player involved in epigenetic reshaping mediated by glutamine breakdown, acting as a co-factor for peroxidases and regulating histone and DNA methylation levels in glutamine breakdown-mediated epigenetic reshaping

doi: 10.1186/s12951-022-01283-2 88 HedlundMStenqvistACNagaevaOKjellbergLWulffMBaranovVet al

The short peptide of the known interactor is called affinity tag and can be, for instance, the His-tag, GST-tag, Strep-tagII, or Twin-Strep-tag

For example, lifestyle modifications in the widest possible context can prolong cognitive longevity

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